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According to the National Institutes of Health, there are approximately 7,000 rare diseases.

In the United States, a disease is considered rare if it is affects fewer than 200,000 Americans. Some countries and the European Union have similar but slightly different definitions.

According to the National Institutes of Health (NIH), there are approximately 7,000 rare diseases affecting between 25 and 30 million Americans. This equates to 1 in 10 Americans, or one on every elevator and four on every bus.

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